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doi: 10.1016/j.cmet.2021.10.008 14 NobelsAvan MarckeCJordanBFVan HulMCaniPD

Acknowledgements We acknowledge the staff of the Department of Neurosurgery who participated in the care of the patient and Professor Jacob Scheinider who prepared the histologic pictures of the case

Seborrheic Keratosis Asymmetric pigmented follicular openings (pseudonetwork) Progression of findings: Early stage: peppering of pigmentation around follicular ostia ( blue-gray dots ) Coalescence of blue-gray dots into polygonal lines and rhomboidal structures Late stage: homogeneous Homogeneous Imaging of the Spleen dark-brown to black blotches blocking the follicular ostia Reflectance confocal microscopy Availability of this technique is limited

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Van Hoof et al

Os resultados obtidos pelos consumidores dependem da dieta, do treino, da ingesto calrica e do estado nutricional inicial