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10.1016/S0165-2427(98)00111-1

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Survival of Her2/neu mice was increased by treatment with CCXC872, a small molecule antagonist targeting CCR2

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They were all treated with the same protocol of extracellular vesicles (EVs) over a 4-week period of time and were evaluated both before and after treatment

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Elevated cAMP levels are believed to possibly activate protein kinase A (PKA), a molecule that appears integral to intracellular signaling

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