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Intestinal macrophages from individual with Crohns disease have reduced selenoprotein expression Utilizing published scRNAseq data from inflamed and non-inflamed colonic biopsies from individuals with CD and control biopsies from 71 donors, changes in macrophage populations and gene expression were assessed

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Identification of novel NRF2-regulated genes by chIP-seq: Influence on retinoid x receptor alpha

In many pathological conditions or artificial interventions, increased extracellular glutamate and disrupted xCT structure or function lead to intracellular GSH depletion, thereby inducing ferroptosis (Yadav et al., 2021)