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2016;15:1145-1160.[PubMed Abstract] - Lens S, Rodriguez-Tajes S, Llovet LP, Maduell F, Londoo MC

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Researchers have adopted a multi-faceted approach, combining studies at the genetic, molecular, organ, and individual levels, to explore the epigenetic changes that methamphetamine use brings to an organism from both micro and macro perspectives
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First, proteins containing N-methylated lysine residues are degraded by lysosomes or proteasomes to release 6-N-trimethyllysine (TML), in which lysine provides the carbon backbone and nitrogen atom of carnitine, whereas methionine provides the methyl group
