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Both ROS-dependent and ROS-independent mechanisms have been shown to contribute to Nrf2 activation, with several phytochemicals and antioxidants identified as potential activators, as shown in a study by Prasad [189]
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CummingsJApostolovaLRabinoviciGDAtriAAisenPGreenbergSet al
Molecular dynamics simulation Root mean square deviation analysis In MD simulation, structural aberrations and stability can be assessed by RMSD analysis, with higher RMSD values indicating conformational oscillations, and lower RMSD values indicating increased structural stability 85
For example, garlic contains allicin, ajoene and thiosulfinates
