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Preclinical studies have shown that co-targeting ferroptosis and pyroptosis (e.g., GPX4 inhibitor + GSDMD activator) can overcome compensatory resistance by engaging complementary cell death mechanisms, amplifying DAMP release, and enhancing T cell infiltration (60, 181)

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BPC-157 consists of 15 amino acids and has been studied for its potential therapeutic effects, particularly in promoting tissue healing and reducing inflammation

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