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The evolution of the ALP gene family has presumably involved the duplication of a primordial tissue-nonspecific ALP gene to create the TNSALP gene and an intermediate IAP gene, followed by additional duplications of the latter to create intestinal, placental, and germ-cell ALP genes
This cofactor acts as a platform that recruits additional transcription factors, such as nuclear respiratory factors 1 (NRF1) and 2 (NRF2) (Kaur and Sharma 2022)
10.1155/2019/8912961 Biomed Res Int
The patient developed the characteristic triad of hypercalcemia, metabolic alkalosis, and acute-on-chronic kidney injury, with improvement in creatinine, calcium, and acid base status after alkaline water was discontinued
Asthaxanthin improves aerobic exercise recovery without affecting heat tolerance in humans
The reported mean values of endogenous MOTS-c serum/plasma concentrations vary widely in the literature
