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Navarro J, Obrador E, Pellicer JA, Aseni M, Via J, Estrela JM

Canizal-Garca M, Olmos-Orizaba BE, Moreno-Jimnez M, Caldern-Corts E, Saavedra-Molina A, Corts-Rojo C (2021) Glutathione peroxidase 2 (Gpx2) preserves mitochondrial function and decreases ROS levels in chronologically aged yeast

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Additionally, it activated the Keap1-Nrf2/HO-1 pathway, which enhanced antioxidant capacity and reversed the abnormal expression of proteins related to iron death, including GPX4, SLC7A11, and FTH1, thus alleviating lung edema and inflammatory cell infiltration (Harada et al., 2014)

It is a component of many multi-subunit oligomers, several of which may be directly implicated in PTSD