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Cryptopleurine targets NF-kappaB pathway, leading to inhibition of gene products associated with cell survival, proliferation, invasion, and angiogenesis

Non-Enzymatic Endogenous Antioxidants Non-enzymatic antioxidants can be classified into endogenous (if cells are able to produce them) and exogenous (if antioxidants need to be ingested through the diet (see Section 3.3))

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Senescence marker protein-30 (SMP30) deficiency impairs myocardium-induced dilation of coronary arterioles associated with reactive oxygen species

GLP-1 Receptor Agonists: The Peptide That Changed Medicine No discussion of peptides for longevity would be complete without addressing GLP-1 receptor agonists, the class of peptide-based drugs that includes semaglutide (Ozempic, Wegovy) and tirzepatide (Zepbound)