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Specifically, thiol concentration is very low and similar to that of disulfides and other thiols occur either as precursors or metabolites of GSH [37]

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For instance, as an increase in drug lipophilicity resulted in a proportionally higher BBB permeation rate, many drug delivery strategies were focused on an increase in lipophilicity of the CNS drugs (25)

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The second type of assay involves measuring oxygen release using Clark-type electrodes (Szczepanczyk et al
