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Key safety principles include strict sterile technique to prevent contamination and infection, proper injection site preparation and rotation, correct needle insertion angle and depth for chosen administration route (IM or SC), slow administration to minimize discomfort, and appropriate post-injection site care and monitoring

New guidelines have expanded the use of B12 injections, particularly in the elderly with cognitive decline, bringing to light an essential approach to well-being in older age

Iron (III) induces aggregation of hyperphosphorylated t and its reduction to iron (II) reverses the aggregation implications in the formation of neurofibrillary tangles of Alzheimer's disease

132 , e158708 (2022)

*Correspondence: Keyu Wang, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Hornstein MD, Young SL