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10.3390/ijms24010095

doi: 10.1183/13993003.00407-2016 99

Given the key roles of the products of these two genes in the cerebral response to ischemia, they are candidate genes which warrant further investigation

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Introduction In 2003, erastin, a novel compound was identified, which showed a selective lethality against human foreskin cells (BJeLR cells) expressing engineered mutated RAS oncogene while using high-throughput screening to find out 23,550 compounds for their ability to eliminate engineered tumorigenic cells (Yang and Stockwell, 2008)

HCT116 (3 groups) or GSTA4-deficient HCT116 (HCT116 GSTA4 ) cells (3 groups) were subcutaneously injected into the flanks of the mice (5 10 6 cells/side) for xenograft tumor growth