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In addition, in research on aging-related muscle atrophy (sarcopenia), it can promote muscle cell proliferation and differentiation, reduce muscle cell apoptosis, and enhance muscle strength and endurance by activating the SIRT1 signaling pathway

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[DOI] [PubMed] [Google Scholar] 65.Wisse BE, Frayo RS, Schwartz MW, Cummings DE

Sometimes symptoms can take years to show up as a deficiency, these symptoms include *Lack of energy *Muscle weakness *Extreme fatigue or tiredness *Yellow eyes *Pale or slightly yellow tinge to skin tone *Pin and needles (paraesthesia) *Shortness of breath and dizziness *Disturbed vision *Sore and or red tongue *Depression *Mouth ulcers *Psychological problems *Changes in mobility *Memory loss and understanding problems Vitamin B12 deficiency can be easily avoided, many people are becoming new to a vegan or vegetarian diet and are unaware of the need to combine sources of plant proteins
