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Resveratrol serves as a protein-substrate interaction stabilizer in human SIRT1 activation (in Eng)

Recent evidence has expanded the role of NNMT beyond clearance of excess vitamin B3

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Eckert MA, Coscia F, Chryplewicz A, Chang JW, Hernandez KM, Pan S, Tienda SM, Nahotko DA, Li G, Blaenovi I, Lastra RR, Curtis M, Yamada SD, Perets R, Mcgregor SM, Andrade J, Fiehn O, Moellering RE, Mann M, Lengyel E (2019) Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts

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