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The full ingredient list: Ingredients: Aqua (Solvent), Tetrahexyldecyl Ascorbate (Antioxidant), Dimethicone (Skin conditioning agent), Glycerin (Humectant), C9-12 Alkane (Emollient), Ascorbyl Glucoside (Skin brightening agent, Silica (Opacifying agent), Pyrus Malus (Apple) Fruit Extract (Skin conditioning agent), Hydrogenated Lecithin (Skin conditioning agent), Polyglyceryl-6 polyricinoleate (Emollient), Mannitol (Skin conditioning agent), Sodium Hydroxide (Solvent), Acrylates/C10-30 Alkyl Acrylate Crosspolymer (Viscosity controlling agent), Xanthan Gum (Emulsion stabilizer), Glutathione (Antioxidant), Ergothioneine (Antioxidant), Oryza Sativa (Rice) Bran Extract (Skin conditioning agent), Hydroethyl Acrylate/Sodium Acryloylmethyl Taurate Copolymer (Dispersing agent), Cetyl Alcohol (Emulsion stabilizer), Caprylyl Glycol (Skin conditioning agent), Lysine Carboxymethyl Cysteinate (Skin conditioning agent), Coco-Caprylate/Caprate (Skin conditioning agent), Tocopherol (Skin conditioning agent), Sodium Citrate (pH adjuster), Sodium Phytate (Chelating agent), Hexylene Glycol (Emulsifier), Ethylhexylglycerin (Skin conditioning agent), Helianthus Annuus (Sunflower) Extract (Emollient), Urea (Humectant), Caprylic/Capric Triglyceride (Skin conditioning agent), Sodium PCA (Skin conditioning agent), Rosmarinus Officinalis (Rosemary) Leaf Extract (Skin conditioning agent), Polysorbate 60 (Surfactant), Sorbitan Isostearate (Surfactant), Trehalose (Humectant), Ascorbic Acid (Skin conditioning agent), Glucose (Solvent), Vanilla Planifolia Fruit Extract (Skin conditioning agent), Polyquaternium-51 (Humectant), Triacetin (Solvent), Sodium Hyaluronate (Skin conditioning agent), Phenoxyethanol (Preservative)

The 2025 Garvey REDEFINE-1 paper in the New England Journal of Medicine reported the Phase 3 obesity trial with four arms combined formulation, semaglutide alone, cagrilintide alone, and placebo providing the most extensive clinical-trial data point currently available for the combination (PMID 40544433)