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However, oral glutathione bioavailability is poorthe GI tract rapidly breaks it down

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The overall strategy of iron chelation therapy is to reduce the unstable iron pool, minimize the production of ROS, and thus prevent lipid peroxidation caused by excessive iron overload

A protein purified from spinach by classical biochemical procedures, considered to be a cytosolic DHAR, had K M values of 2.5 mM and 70 M for GSH and DHA, respectively (Hossain and Asada, 1984)

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Concentrations reached in the brain via oral dosing of 4,000 mg/kg body weight were about 2 M/g [42]