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Pathology of peliosis

Froissard P, Monrocq H, Duval D

Ceramide synthesis was indeed required for the effect of palmitate addition on the activity of AKT/PKB since pharmacological inhibition of ceramide synthesis or siRNA-mediated knockdown of several enzymes required for ceramide biosynthesis (serine palmitoyltransferase, ceramide synthases, or dihydroceramide desaturase) completely blocks the effects of palmitate on insulin signaling

The rise of ALT, AST, ALP, cholesterol, triglyceride, total bilirubin, LDH, urea, creatinine, and creatinine kinase were considered

doi: 10.1186/s12944-019-1150-0 113