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Description
Excess tumor-derived lactate leads to lactic acid accumulation, which impairs CD8 + T cell effector functions through intracellular acidification and inhibition of glycolytic enzymes such as GAPDH
In addition, unfractionated heparin exhibits anti-inflammatory, mucolytic and anti-viral properties and, specifically, it has been demonstrated to inactivate the SARS-CoV-2 virus and prevent its entry into mammalian cells, thereby inhibiting pulmonary infection caused by SARS-CoV-2 [15]
Hassan, Z.U
(2021) 7:e06372
Veter Med
10.1002/ejoc.202100240 4 BrownA.BrillJ.AminiR.NurmiC.LiY
