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doi: 10.2337/db19-1046

GLP-1 agonists produce dramatic weight loss (averaging 15-20% total body weight) primarily through central appetite suppression, eliminating hunger and creating pharmaceutical satiety

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If fatigue persists beyond this period or worsens, medical review is recommended to identify underlying causes

Karczewski KJ, Francioli LC, Tiao G, Cummings BB, Alfoldi J, Wang Q, et al

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