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The in vivo anti-inflammatory actions of omega-3 PUFA are consistent with the insulin sensitizing effects of these lipids and are completely dependent on the presence of FFAR4/GPR120

Bodda et al

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Vitamin A from -carotene is not known to increase the risk of birth defects (66), although the safety of high-dose -carotene supplements in pregnancy has not been well studied

Kidney Concerns (in pre-existing conditions) : Although generally safe for healthy individuals, those with kidney problems should be cautious

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