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Peroxisome proliferator-activated receptor alpha induction of uncoupling protein 2 protects against acetaminophen-induced liver toxicity

While the cells treated with Ru(II)-OH or NP2 in a 1% O 2 atmosphere were confluent and alive, the cell treated with NP4 had a strongly reduced cell population and a mixture of living and dead cells comparable to the treatment with these nanoparticles in a 21% O 2 atmosphere (Fig

This is a crucial safety question that requires clear, evidence-based guidance

When these irritate the brain, patients develop hepatic encephalopathy a serious condition that causes confusion, coma, seizures and, finally, life-threatening swelling of the brain)

Inflammation Research, 57(5), 205210
