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Chronic alcohol consumption leads to a decrease in the hepatic population of conventional NK cells and impairs their cytolytic function, as evidenced by the reduced expression of natural killer group 2, member D (NKG2D), tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), and IFN- [119,120,121]
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10.3748/wjg.v24.i48.5462 17 DuzelA.VlainicJ.AntunovicM.MalekinusicD.VrdoljakB.SamaraM.et al (2017)
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29,30 The activated CD8 + T cells differentiate into CTLs to further induce cellular immunity
Liver disease progression in patients with alpha-1 antitrypsin deficiency and protease inhibitor ZZ genotype with or without lung disease
