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ZIP13 dysregulation has further been implicated in myocardial ischemiareperfusion injury and broader connective-tissue pathologies 63,143

Reprogramming of mitochondrial serine metabolism in colorectal cancer facilitates purine nucleotide biosynthesis and enables drug-resistant cells to prevent the accumulation of drug-induced DNA damage, thereby promoting resistance to 5-FU (54)

Expression of -glutamylcysteine synthetase (-GCS) and Multidrug Resistance-associated Protein (MRP), but not human canalicular Multispecific Organic Anion Transporter (cMOAT), genes correlates with exposure of human lung cancers to platinum drugs

Protective effect of melatonin-supported adipose-derived mesenchymal stem cells against small bowel ischemia-reperfusion injury in rat

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It is also carcinogenic