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AD is a heterogeneous disease and this discrepancy between these studies could be attributed to the broad spectrum of genotype and phenotype as well as various interactions with environmental factors in AD [128]

BMC Psychiatry 23 , 431 (2023)

It plays a vital role in wound healing, angiogenesis, and cellular remodeling, and is studied extensively for its influence on collagen synthesis, anti-inflammatory signaling, and gene expression associated with skin and organ repair

J Biol Chem 272:3078030786

doi: 10.1097/TP.0000000000004838

RhoA and ROCK are important downstream effector molecules of ARHGEF3, directly influencing the assembly of actin bundles (Fig