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For instance, 4-hydroxynonenal treatment reduces tight junction protein expression in the colon, boosts bacterial movement from the gut to circulation, and intensifies Toll-like receptor-4 signaling activation (37)

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When administered in doses of 50 and 100 mg/kg to mice, DEAB increased the blood acetaldehyde concentration and inhibited the fraction of ethanol converted to acetate by 32.5 and 67.5%, respectively (Mahmoud et al., 1993)