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Usually, patients with OC exhibit non-specific symptoms such as abdominal distension, pain, appetite loss, or increased frequency of urination during early development
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The toxic effect of methanol on the optic nerve and the retina may occur through the influence on the expression of key cytoskeleton proteinsactins and tubulins (beta-actin, beta-tubulin) conditioning the maintenance of the proper structure of cells, as well as cell signaling and regulating the process of apoptosis
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10.1016/j.ejca.2011.08.009 85 von MinckwitzG.SchneeweissA.LoiblS.SalatC.DenkertC.RezaiM.et al (2014)
