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This allows us to identify a novel mutational signature that is suppressed by the TLS polymerase Pol and is mainly observed in liver and kidney (Fig

For example, in the mouse model of PD induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), Coenzyme Q10 (CoQ10) attenuated the generation of oxidants, elevated striatal dopamine levels, and increased the number of striatal mitochondria, the synthesis rate of ATP, and the activity of striatal complex I [6]

Disclosure and potential conflicts of interest: The authors declare that they have no conflicts of interest

To confirm this strong ECM-binding activity in vivo, we then tested the retention of the engineered factors after intradermal administration

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5 Multiple alignment of cysteine-rich squash proteinase inhibitors
