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Applications in Biotechnology Yeast extract contains abundant amino acids, vitamins, nucleosides, polypeptides and minerals and is therefore an ideal nutrient growth medium for both laboratory and industrial microbial fermentation, especially for auxotrophic strains [90]

Not only can many types of PTMs accumulate in mitochondria [85], but they can also downregulate the expression of or inactivate mitochondrial deacetylases like sirtuin 3 (SIRT3) [114,115,116,117], sirtuin 4 (SIRT4) [118,119,120,121], and sirtuin 5 (SIRT5) [8, 48108, 109, 117, 122, 123] in the context of ALD [124, 125], MASLD [51, 126, 127], and other conditions [128]

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[DOI] [PMC free article] [PubMed] [Google Scholar] [166].Liu Y, Lu F, Kang L, Wang Z, Wang Y, Pirfenidone attenuates bleomycin-induced pulmonary fibrosis in mice by regulating Nrf2/Bach1 equilibrium

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