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This steric hinderance means that important RTK-mediated phosphorylation of Tyr is hindered, with the consequence that neuronal survival could be affected (5, 40)

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Subsequent studies demonstrated that both the PKD and CAF domains are required for amyloid formation in vivo 53,54

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doi: 10.1186/s12943-022-01569-x 104 RuwanpuraSMThomasBJBardinPG

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