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Despite challenges in achieving consistent BBB penetration, several nanoparticle types, such as lipid- and polymer-based nanoparticles, show strong translational potential

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Food Nutr Sci 03(10):13541374 Doreddula SK, Bonam SR, Gaddam DP, Desu BS, Ramarao N, Pandy V (2014) Phytochemical analysis, antioxidant, antistress, and nootropic activities of aqueous and methanolic seed extracts of ladys finger ( Abelmoschus esculentus L.) in mice

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Furthermore, the bloodbrain barrier (BBB) significantly limits the bioavailability of these drugs, as it prevents effective doses from reaching the brain