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the NOD2 protein can activate the immune system by triggering NF- B and can negatively regulate the Toll-like receptor-mediated T-helper type 1 response, thereby increasing susceptibility to infection [43, 44]

Sodium butyrate ameliorates the cognitive impairment of Alzheimers disease by regulating the metabolism of astrocytes

10.1016/j.cellimm.2016.08.008 27 ParkerC

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The transition of microglia from a resting quiescent state to an activated immune-effector state is controlled by intracellular Ca2+

Wang JM, Mauro M, Edwards SL, Oatley SJ, Fishel LA, Ashford VA, et al