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The deep pocket appears to allow binding of polyphenols without catalytic activity

This is where inflammation-modulating peptides become relevant

Damaged mitochondrial structures (red arrows) were seen in the paclitaxel (PAC) group and not in the paclitaxel plus curcumin (Cur) group

A conserved dual function of the conserved lysine residue for redox catalysis is also supported by previous studies: Lys19 of human Grx1 and Lys8 of NrdH-redoxin from C

McConnell HL, Li Z, Woltjer RL, Mishra A (2019) Astrocyte dysfunction and neurovascular impairment in neurological disorders: correlation or causation