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[DOI] [PMC free article] [PubMed] [Google Scholar] 203.Frezza M, Padova C di, Pozzato G, Terpin M, Baraona E, Lieber CS

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In the liver, they both have metabolic regulation actions, but IRS-2 has a more profound role in lipid metabolism [121]

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originally for diabetes Mounjaro (tirzepatide): Dual-acting injection for diabetes and obesity Saxenda (liraglutide): Daily injection approved for weight loss Zepbound (tirzepatide): Newly approved for chronic weight management These medications mimic hormones like GLP-1 , helping you feel fuller longer, eat less, and lose weight gradually over time