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Cleavable linkers are designed to release the cytotoxic drug in response to specific environmental conditions within tumor cells, such as changes in pH, redox potential, or the presence of lysosomal enzymes

Int J Clin Exp Med [Internet]

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Furthermore, another set of transcripts had shorter open reading frame (ORF) in HL compared to R phase (Figure S6), which could result in truncated proteins produced in HL-treated leaves