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Furthermore, specific molecular mechanisms by which diabetes disrupts spermatogenesisparticularly in areas such as epigenetic regulation, mitochondrial dysfunction, and ER stressremain inadequately explored

The administration of GLP-1RA or exendin-4 to rats fed a high-fat diet resulted in an increase in the OPG/RANKL ratio and a reduction in the degree of bone loss
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IGF-1 LR3 appears to enhance muscle growth, accelerate tissue repair, and improve recovery through activation of the Akt/mTOR pathway, a key driver of protein synthesis
