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Proc R Soc B Biol Sci
GHK-Cu topical use can sometimes worsen skin conditions initially

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In Cohort 1, 25 WT and 25 RAMP1/3 KO male mice aged 1220 weeks old were injected intraperitoneally after a 12-hour fast with vehicle, sCT at doses of 3 or 150 nmol/kg, or Cagrilintide at a dose of3 nmol/kg
Its a small tripeptide bound to a copper ion, and it was first identified in human plasma decades ago
