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In addition, zinc protects cells against oxidative damage, acts in the stabilization of membranes and inhibits the enzyme nicotinamide adenine dinucleotide phosphate oxidase (NADPH-Oxidase)

Expanded view Figure EV1 Effects of Fer-1 and NAC on tumor ferroptosis and tumor control induced by poly(I:C) plus RT in HCC mice model

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Although mammals lack a biosynthetic pathway for ERGO, the carnitine/organic cation transporter OCTN1/SLC22A4, which transports ERGO in vivo , is expressed throughout the body, and ERGO is distributed to various organs after oral intake