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Two enzymes among several, including fumarase A, which harbors an FeS cluster, and carbonic anhydrase II, which is a Zn II enzyme (Section 4.3.4), were projected to be undermetalated upon holomycin treatment

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Table 8

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Combined with a GLP-1 receptor agonist, it has a more significant effect on glucose and body weight effects such as: boosted weight loss, improvements in cardiometabolic measures and reduced appetite
