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Iron accumulation from various sources significantly contributes to AS and vascular endothelial cell (VEC) ferroptosis

The liver has the major responsibility for detoxification, and GSH is the cornerstone of this process

doi: 10.1039/D5FO01780G 329 Kamierczak-SiedleckaKRuszkowskiJFicMFolwarskiMMakarewiczW

The same pattern was demonstrated when NAC was administered only or postnatally

It is important to note that these strategies are not at this time FDA-approved to prevent, mitigate, treat, or cure uterine fibroids and should not be confused as such

Livers were surgically excised prior to assessment of GPx activity and were thoroughly rinsed with 0.9% (w/v) NaCl to remove blood and contaminants
