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Secreted IL-13 from activated Th2 cells can influence the release of TGF-1 from activated macrophages through the JNK signaling pathway, regulate fibroblast proliferation and differentiation through the JNK and AKT signaling pathway as well and promote the expression of -SMA and collagen I that leads to the development of fibrosis 71

1,25-Dihydroxyvitamin D3 prevents toluene diisocyanate-induced airway epithelial barrier disruption

[DOI] [PMC free article] [PubMed] [Google Scholar] 72.McDaniel M.A., Maier S.F., Einstein G.O

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