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A synergistic, multitargeted approach may eventually transform this devastating disease into a controllable chronic one

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Duobamycin hydroxybenzamide-azaindole (DUBA) exhibits potent efficacy as a DNA-damaging agent through the tight binding of its cyclopropane ring to the DNA cleavage groove and the alkylation of adenine at the N 3 site

Mei M, Liu M, Mei Y, Zhao J, Li Y
