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Impaired B cell function during viral infections due to PTEN-mediated inhibition of the PI3K pathway

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Developed BBB-targeted NPs induced P-gp downregulation and consequent increase on P-gp substrate permeability, revealing their ability to modulate drug efflux at the BBB

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Osteoporosis High blood concentrations of homocysteine may affect bone remodeling by increasing bone resorption (breakdown), decreasing bone formation, and reducing bone blood flow