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We conducted a metabolome-wide association analysis to investigate the link between the serum metabolome and depressed mood (DM) in 1411 participants of the KORA (Cooperative Health Research in the Augsburg Region) F4 study (discovery cohort)

The effect on pigmentation is transient, so you would need to continue using glutathione to maintain the skin-whitening effect.A scientific review of multiple studies confirmed that the use of glutathione results in skin lightening.The same studies also show that glutathione doesnt just lighten skin, but it improves skin elasticity and decreases wrinkles.