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Lipophillic agents are added to the lipid mixture, or encapsulated (optionally as a post manufacturing process in the hospital pharmacy) using the active loading procedure with liposomes pre-f lled with e.g., ammonium sulfate or calcium acetate

Pharmaceutical Research, 16 , 1412-1416

That waste needs water to be moved out of the body through the kidneys and skin

PMID: 32213703 | doi:10.1172/jci.insight.133429 Kruse T et al

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Because of the enhanced bioavailability and decreased clearance of the nanoparticles, it is thought that a larger aspect ratio of the particles corresponds with increased cytotoxicity