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in the central nervous system, GLP-1 receptors on hypothalamic (arcuate nucleus) and hindbrain (nucleus tractus solitarius and area postrema) neurons drive the reduction in food intake that underlies weight loss

Lateral Pharma Kwon DR, Park GY

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In a cervical cancer cell line (HeLa), the compound reduced cell proliferation in a concentration- and time-dependent way and lowered expression of phospho-Akt and SIRT1, two proteins tied to tumor progression, while a non-cancer reference cell line was less affected

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Clinicopathological and prognostic significance of c-Met overexpression in breast cancer