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AstraZeneca Lead assets: Elecoglipron, an oral GLP-1RA candidate Metabolic focus: Obesity, overweight, type 2 diabetes and cardiometabolic disease AstraZeneca is developing elecoglipron as a once-daily GLP-1RA pill for obesity and type 2 diabetes

Zhang, J., et al

The peptide proceeded through Phase IIb clinical trials for obesity, where it demonstrated favourable safety but failed to meet weight-loss endpoints at the doses tested

We always recommend getting labs done to determine if you are truly deficient in B12 and if supplementation is necessary

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In order to effectively lose weight, individuals need to maintain a calorie-deficient diet and a regular exercise regimen to get their body to use the stored fat as energy rather than newly ingested food