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B12 supplements can interact with certain medicines, including: Chloramphenicol (Chloromycetin Sodium Succinate) Proton pump inhibitors Metformin (Glucophage, Glumetza, Riomet) Gastric acid inhibitors If youre taking any of these medications, talk to your doctor or pharmacist before starting a B12 supplement

Symptoms of B12 deficiency include the following (MHRA, 2022): Neuropathy

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If you tend to have digestive problems, a B12 deficiency can make them worse

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The peptide simply does not interact with the receptors and pathways that stimulate IGF-1 production