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Arch.Pediatr 2012;19(2):184-193

Conversely, taking larger doses for prolonged periods of time had adverse effects on anaerobic sprint performance.[/box] References: J Int Soc Sports Nutr

(2011) 124:84151.e2

Acetyl-L-carnitine supplementation to old rats partially reverts the age-related mitochondrial decay of soleus muscle by activating peroxisome proliferator-activated receptor gamma coactivator-1alpha-dependent mitochondrial biogenesis

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The different mutations in SLC22A5 probably give rise to differences in severity/onset of the disease
