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Activation of the kynurenine pathways is often associated with reduced free circulating (reviewed by Hazrati et al., 2024) and brain tryptophan levels (Hazrati et al., 2024

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Differential effects of trovafloxacin on TNF- and IL-6 profiles in a rat hepatocyte-Kupffer cell coculture system

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Nat Rev Dis Primers 2:16047