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The inhibition of methylation enzymes (DNMTs) with different molecules such as azacitidine and decitabine (drugs used in oncology), can be useful in modifying the malignant phenotype of the cells through re-expression of tumor suppressor genes [8, 47, 48]

cerevisiae D7 yeast cells demonstrating a 70% decrease in cell survival compared to the control

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doi: 10.1016/0092-8674(93)90719-7

doi: 10.1177/11795514241249013